I feel Serena would be the winner in the women's category because she is deserving and an experienced player. Being a top-seeded player is not easy after all.
In the male's category there is every likelihood that both of the players can win but as per the Wimbledon tourna.ent wherein Novak recently won over both Andy Murray and Roger Federer. Djokovic, the no.1 in the world in singles category won against Federer in the Wimbledon final. Therefore, looking at the statistics of Djokovic I feel he is desperate and deserving to win against his competitors.