We all know that Kamal Hasan is a person a bit apart from the rest, where he does a lot of creative thinking and dons variety roles. Here are some roles which are of significance as they proved to be later.
1. In 1978, Kamal's Tamil movie "Sivappu Rojakal" was released in which he plays the role of a Psychopath killer (femicide). A year later, a man, "Psycho Raman" was caught for brutally murdering people, specially women.

2) In 1996 many Indians were cheated by finance companies. Kamal Hassan had clearly depicted this in his movie "Mahanadhi" which was released in 1994.

3) In "Hey Ram"(2000), there are few scenes relating to Hindu Muslim clashes. 2 years later, Godhra (Gujarat riots) incident happened.

4) He used a word called 'tsunami' in his movie "Anbe Sivam"(2003).This word was unknown to many people before. In 2004, the 'tsunami' stuck the country's eastern coast with many people losing their lives.

5) In his latest movie "Dasavatharam" in 2008 he mentions about a deadly virus, which spread via air, that may destroy the world. And in 2009 we have the Swine Flu that spreads through air. And to add to it,in this movie Kamal develops a bio weapon and finds out the deadly effect of the virus in a lab in America. After an year, the first case of Swine Flu was detected in Mexico (America).